What Interstate Highways serve Denver, CO?

I-25 north and south connecting to Albuquerque and Cheyenne.
I-70 east and west connecting to the Great Plains and the Rockies.
I-76 northeast connecting to I-80 in eastern Nebraska.
As well as bypass routes I-225 and I-270.  Both on the east side of town, connecting I-70 to I-25 (one north of downtown, the other south).

There are several. check it out !

I39 east west and I48 / I21 north south.  The beautiful Pothead state.

I 70 runs east and west and into ski country.

you might be able to get that info online