What is the best book you have ever read?

"The God Delusion" by Richard Dawkins is one of many.

I have read thousands of books and enjoyed most.

The Last of the Mohecans.    Dr. Zhivago.   Asimov's Foundation Trilogy

Uncle Tom's Cabin.

A Prayer for Owen Meany by John Irving (I’d recommend this book to anyone)
The Executioner’s Song by Norman Mailer (The writing, the effort, the structure, everything gets an A)
Fight Club by Chuck Palahniuk (wild ride)
Catch 22 by Joseph Heller (a totally different wild ride, worth any extra effort it may take)
Helter Skelter by Vincent Bugliosi (Absolutely fascinating)
Middlesex by Jeffrey Eugenides (Drops off in the last 20%, but the first 80% is so well written it doesn’t matter)
Gathering of Waters by Bernice L. McFadden (I fell in love with this book on the first page. Painfully beautiful)
The Miracle Life of Edgar Mint by Brady Udall (People and place wrapped in excellent writing)

EDIT: aside from the people who didn't actually answer the question, how can you give thumbs down to someone's personal favorites?? Every single answer has a thumbs down. Total bullshit.

1984 George Orwell.

I like Gulliver's Travels by Jonathan Swift.  Babbitt by Sinclair Lewis.  and 'God's Coach' by Skip Bayliss.  

Flowers for Algernon by Daniel Keys 
(Highly recommend)

A Prayer for Owen Meany by John Irving
The Wolf Hall etc trilogy by Hilary Mantel
The Roads to Freedom series by Jean-Paul Sartre
Narziss and Goldmund by Hermann Hesse.
The Peloponnesian War by Thucydides - believe me this is as relevant today as it was in 500BCE.

"Childhood's End" - Arthur C. Clarke
"To Serve Man" - Damon Knight
"Anna Karenina" - Leo Tolstoy
"The Deathbird" - Harlan Ellison
"The Brothers Karmazov" - Fyodor Dostoevsky

Norwegian Wood is my favourite book.

There are 100's, but I consider "Brave New World", "1984" & "A Clockwork Orange" as perhaps the most important & prescient books written in the 20th C.  

Catch - 22 is my favorite.

Don Quixote.    

Destroyermen series by Taylor Anderson

The Koban series by Stephen W. Bennett.

I have read too many to have a favourite.  Authors I would re-read: Charles Dickens, Muriel Spark, EF Benson, Kate Atkinson: a rather catholic (or in one case Catholic) selection, but that's the fun of books.

To Kill a Mockingbird--the only required reading in school that was a pleasure
The Road
Catch-22
Cryptonomicon
The Gargoyle

The Bible is the best book I have ever read.  Quo Vadis was a great book, too.

Bury my heart at wounded knee

I really enjoyed The Lord of the rings series for the amazing world, characters, writing and fictional languages. 

I love 1984 too, Orwell's dystopian world is fascinating and the book is full of great dialogue. 

I enjoyed Pride and Prejudice for the characters and the way the characters redeem themselves in the end. 

A clockwork Orange was a great read too, some of the dialogue is Russian, some sounds Shakespearean and some of it is completely made up. It's also one of those books you can read quickly and reflect upon after.  

These are just some of my favourites.

Stranger in a Strange Land, by Robert Heinlein,  Ring Around the Sun, by Clifford D. Simak, Self help books by Karen Horny, I Never Promised You a Rose Garden, by Joanne Greenberg,  Crime and Punishment, by Fyodor Dostoevsky.  The Crhonicles of Narnia, by C. S. Lewis

"Little, Big," by John Crowley. 

Zelazny's Nine Princes in Amber and Lord of Light. Marion Zimmer Bradley's The Mists of Avalon and Darkover. John Crowley's Little Big. Wind in the Willows. Wuthering Heights. The Golden A ss of Lucius Apuleius and Ovid's Metamorphoses. Julian and Ancient Evenings.

The Bible (KJV)
A Wrinkle In Time
Jules Verne's Books
  Mysterious Island; 20,000 Leagues Under the Sea; From Earth to the Moon;
  (a few others)
Charles Dickens Books 
The Celestine Prophecy with The Tenth Insight
Countless others way to numerous to account for here

Zorba the Greek by Nikos Kazantzakis.  Also, Asimov's foundation trilogy.

Atlas Shrugged

The Holy Bible the King James Version

War and Peace

the combined works of William Shakespeare

Catch Me If You Can......................

The Big Sleep-Raymond Chandler.
The Sat***c Verses - S Rushdie.

Oryx and Crake - M Atwood.

Siddhartha by Herman Hesse
Candide by  Voltaire

Five of my favourite classics:

Anna Karenina - Lev Tolstoy
Middlemarch - George Eliot
Absalom! Absalom! - William Faulkner
Cold Comfort Farm - Stella Gibbons
Brave New World - Aldous Huxley

Five of my favourite modern novels (second half of 20th century or later):

Illywhacker - Peter Carey
The Famished Road - Ben Okri
The Essex Serpent - Sarah Perry
Border Crossing - Pat Barker
Wolf Hall - Hilary Mantel.

The best book I have read was The Time Machine by H.G. Welles.

Beanie Forsythe and the Temple of Doom

Man's Search for Meaning, They Thought They Were Free, Hitler's Benificieries, Of Mice and Men, Wind Over Stonehenge.

One Flew Over The Cuckoo's Nest by Ken Keasy

Clear And Present Danger by Tom Clancy

The Sum Of All Fears by Tom Clancy

Red Rabbit by Tom Clancy

Against All Enemies by Tom Clancy with Peter Telep

The Spy Who Came In From The Cold by John Le Carre

Tinker Tailor Soldier by John Le Carre

Larry Bond's Red Dragon Rising series by Larry Bond with Jim DeFelice  

Walt Disney: An American Original by Bob Thomas

The Disney Book: A Celebration of the World of Disney by Jim Fanning

The Anxiety and Phobia Workbook Fourth Edition by Edmund J. Bourne PhD 

I don't really like to read books because I find it extremely boring!  I did read a few books in school and college, but they were all very depressing! 

THE HOLY QURAN. Which is The holy Book of God.

The Holy Bible....Greatest book in existence

I have read thousands of books and enjoyed most.,,,,,,,,,,,

Fiction?   Probably "Slaughterhouse-Five" by Kurt Vonnegut, Jr.

Non-fiction?  "Nomadland" by Jessica Bruder.

The two books I can always read no matter what is Enclave by Ann McGuire and Shiver. But I recently read Scythe by Neal Shusterman and it's on my top five list. 

I'm not sure I can ever say a specific book is the best I've ever read, but World War Z (Max Brooks) and Hover Car Racer (Matthew Reilly) are certainly up there, as is the original Mistborn Trilogy (Brandon Sanderson)

I have read way to many good books to claim any single one as a favorite...

About 1500 if you are wondering....

N.Shadows

To Sleep in a Sea of Stars

Book by Christopher Paolini

"All I Really Need to Know I Learned in Kindergarten." Robert Fulghum. 

The Family Corleone
It was a deal I couldn't refuse.

A war to be won: Fighting the second world war

best book , easy it How to make friends and influance people by Dale Carnegie , very accurate and true . you should read it if your into sales .

confessions of a lady-boy.................
oh yes 
oh yes

Its hard to say.  There are so many great ones like:

King of the Wind
The Princess and the Goblin
David and the Phoenix
The Complete Book of Dragons
A Little Princess
The Secret Garden
The Forbidden Door
The Phantom Toll Booth
The Door in the Wall
Eight Cousins
Library Lion
The Black Stallion
Skellig
Chronicles of Narnia
Lord of the Rings
Legend of Huma

I have read thousands of books and enjoyed most.

Coral island i was 15 

Short Stories But True by Sabino Rosa
is wonderful and you can find it even likes e-book