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https://www.dailymail.co.uk/health/article-1200287/Daily-dose-baking-soda-stop-kidney-patients-needing-dialysis.html
A daily dose of baking soda could transform the lives of patients with failing kidneys, scientists claim.
A British team says the kitchen product - also known as sodium bicarbonate - can dramatically slow the progress of chronic kidney disease.
The household staple, used for baking, cleaning, bee stings and acid indigestion, is so effective it could prevent patients from needing dialysis, the results show.
Study leader Magdi Yaqoob, Professor of Renal Medicine at the Royal London Hospital, said: 'It's amazing.
'This is the first randomised controlled study of its kind.'
'A simple remedy like sodium bicarbonate (baking soda), when used appropriately, can be very effective.
Around three million people in the UK suffer from chronic kidney disease.
The condition ranges in severity from a mild degree of poor functioning to complete kidney failure.
Seriously affected patients may have to spend time each day on a dialysis machine which takes over the function of the kidneys.
An estimated 37,800 patients in the UK receive renal replacement therapy, which involves dialysis or a kidney transplant.
The cost of looking after kidney failure patients costs the NHS £30,000 a year - soaking up 3 per cent of the entire NHS budget.
Doctors have long wondered about the potential value of baking soda for kidney disease patients who commonly suffer from low bicarbonate levels, a condition called metabolic acidosis.
The pilot study conducted at the Royal London Hospital, Whitechapel, was the first controlled test of the treatment in a clinical setting.
Researchers studied 134 patients with advanced chronic kidney disease and metabolic acidosis.
One group was randomly allocated a small daily dose of sodium bicarbonate in tablet form in addition to their usual care.
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Over a period of one year, the kidney function of these patients declined about two thirds more slowly than that of individuals not given the tablets. In fact, their rate of decline was little different from what would be expected with normal ageing.
Rapid progression of kidney disease occurred in just 9 per cent of patients given baking soda compared with 45 per cent of the non-treated group.
Patients taking sodium bicarbonate tablets were also less likely to develop end-stage renal disease requiring dialysis.
The findings were published yesterday in the Journal of the American Society of Nephrology.
Study leader Magdi Yaqoob, Professor of Renal Medicine at the Royal London Hospital, said: 'This study shows baking soda can be useful for people with kidney failure. That is, as long as the dose is regulated and under supervision.
'What happens is the inflammation of kidney is prevented by baking soda because a chemical reaction takes place limiting ammonia production in the kidney.
'This cheap and simple strategy also improves patients' nutritional well-being and has the potential to improve quality of life and of course a clinical outcome that can remove the need for dialysis.
'Baking soda is not classed as a drug so this study has never been tried before.'
The scientists pointed out that their research was limited by not having a 'placebo group' of patients receiving a 'dummy' treatment.
'Our results will need validation in a multi-centre study,' said Prof Yaqoob.
Dr Kevin Harris, senior medical adviser at Kidney Research UK, welcomed the study.
He said it should 'help to inform future guidelines and assist our research fellows who are currently working extremely hard to ultimately find a cure.'
科學家聲稱,每日服用小蘇打可以改變腎臟衰竭患者的生活。
一個英國團隊表示,廚房產品 - 也稱為碳酸氫鈉 - 可以顯著減緩慢性腎病的進展。
結果顯示,用於烘焙,清潔,蜂蜇和酸性消化不良的家用主食非常有效,可以防止患者需要透析。
研究負責人,皇家倫敦醫院腎臟醫學教授Magdi Yaqoob說:“這太棒了。
“這是第一次同類隨機對照研究。”
“如果使用得當,一種簡單的補救方法,如碳酸氫鈉(小蘇打),可能非常有效。
英國約有300萬人患有慢性腎病。
該病症的嚴重程度範圍從輕度功能不良到完全腎衰竭。
嚴重受影響的患者可能不得不每天花在接受腎臟功能的透析機上。
據估計,英國有37,800名患者接受腎臟替代治療,包括透析或腎移植。
照顧腎功能衰竭患者的費用每年花費3萬英鎊 - 佔整個NHS預算的3%。
醫生們長期以來一直想知道小蘇打對於通常患有低碳酸氫鹽水平的腎病患者的潛在價值,這種情況稱為代謝性酸中毒。
在Whitechapel的倫敦皇家醫院進行的試點研究是臨床治療中首次對照試驗。
研究人員研究了134例晚期慢性腎病和代謝性酸中毒患者。
除了常規護理外,一組隨機分配片劑形式的每日小劑量碳酸氫鈉。
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在一年的時間內,這些患者的腎功能比未服用片劑的患者慢了約三分之二。事實上,他們的下降速度與正常老化的預期差別不大。
只有9%的小蘇打患者發生腎臟疾病的快速進展,而非治療組的這一比例為45%。
服用碳酸氫鈉片劑的患者也不太可能患上需要透析的終末期腎病。
該研究結果於昨天發表在“美國腎髒病學會雜誌”上。
研究負責人,倫敦皇家醫院腎臟醫學教授Magdi Yaqoob說:“這項研究顯示,小蘇打可能對腎功能衰竭患者有用。也就是說,只要劑量受到監管並受到監督。
“發生的事情是通過小蘇打防止腎臟發炎,因為發生化學反應限制了腎臟中的氨生成。
“這種廉價而簡單的策略還可以改善患者的營養狀況,並有可能改善生活質量,當然還有可以消除透析需求的臨床結果。
“小蘇打不被歸類為藥物,所以這項研究以前從未嘗試過。”
科學家指出,他們的研究受限於沒有“安慰劑組”的患者接受“虛擬”治療。
“我們的結果需要在多中心研究中進行驗證,”Yaqoob教授說。
英國腎臟研究中心的高級醫療顧問Kevin Harris博士對這項研究表示歡迎。
他說,它應該“有助於為未來的指導方針提供信息,並協助我們的研究人員,
他們目前正努力工作,最終找到治療方法。”
BY google translate
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