What is the entire reaction mechanism for 1-butanol with ammonium bromide in the presence of sulfuric acid?
回答 (1)
The mechanism is SN2. As -OH is a very poor leaving group, concentrated H₂SO₄ is used to protonated the -OH group to become -OH₂⁺ which is a much better leaving group. Then, Br⁻ ion in ammonium bromide acts as a nucleophile to substitute water.
The mechanism is shown below.
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