2000 S10 2WD leaks oil bad on the left front near the radiator support. Whats broken?

Transmission fluid cooler line is loose or the cooler itself is damaged and needs replacing.

If it's an automatic the leak may be the ATF cooler lines. Have you checked your ATF level lately? if it is the ATF lines they can rupture and blow all the ATF out of the tranny before you know it and destroy the transmission. Once it slips it's junk. better get it repaired immediately!