Yes. Even NASA estimates that humans will likely never come into direct contact with another intelligent alien lifeform. Like ever... Why?
For us and that lifeform to meet that means that they would just have to coincidentally exist at the same time in out galaxy's 13.2 billion year history as we do.
They would also have to just coincidentally live in a star system close enough so that traveling the vast interstellar distances could at least be plausable. Remember, space is BIG. Even traveling at the speed of light (and nothing with mass can travel that fast) it takes years or decades to reach just the handful of stars nearest to us.
Both of these coincidences are very unlikely on their own, let alone together.
More likely, we could pick up some of their electromagnetic signals of find indirect evidence from observing their star system with telescopes. But that's about as close as it'll be.
It is possible that we'll find alien life here within our solar system but it would be simple life like bacteria. The best candidates for that are Mars, Jupiter's moons Europa and Ganymede, and Saturn's moons Titan and Enceladus.