How would you prepare 2-butanol from 1-propanol?

2016-07-18 5:13 am

回答 (1)

2016-07-18 6:58 am
Step 1 :
Convert CH₃CH₂CH₂OH to CH₃CH₂CHO by heating with potassium dichromate solution acidified with dilute sulfuric acid, and collect the aldehyde product by distillation simultaneously.

Step 2 :
Convert CH₃CH₂CHO to CH₃CH₂CH(OH)CH₃ by treating with CH₃MgCl in dry ether (to form CH₃CH₂CH(OMgBr)CH₃ first) followed by hydrolysis with a weak acid.


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