Can anyone help with my blood test results?

2016-01-01 6:41 pm
Any haematologists out there? I have a ferritin level of 360, which I know is high. But my transferrin saturation is 16 per cent and blood iron level is 11, which I think are on the low side? Being referred to haematology as my GP doesn't understand this - any ideas what's going on?

Thank you
更新1:

Any haematologists out there? I have a ferritin level of 360, which I know is high. But my transferrin saturation is 16 per cent and blood iron level is 11, which I think are on the low side? Being referred to haematology as my GP doesn't understand this - any ideas what's going on? Thank you Sorry - just seen answers below. My CRP was checked and was in normal range (can't remember number) Haemoglobin is 11

回答 (3)

2016-01-01 7:33 pm
✔ 最佳答案
Let's start off first by saying that the gold standard for determining iron deficiency is not the ferritin level but a bone marrow biopsy and checking for iron stores with special stains.

Although ferritin has been a convenient way to check for iron stores it has been known to be falsely elevated due to inflammation. I would have checked that by doing a sedrate or CRP to evaluate the contributions inflammation has. Ferritin is decreased in iron deficiency anemia while ferritin is increased in anemia of chronic disease.

The iron and percent saturation testing are low and that finding can be seen in iron deficiency anemia along with anemia of chronic disease. A history in searching for conditions associated with anemia of chronic disease is important. When it comes to iron studies IDA has a high total iron binding capacity whereas anemia of chronic disease it is low. That is one way to distinguish the two.

A blood smear would be informational with regards to the entire CBC results.

Botom line here is a check for inflammatory indicators is probably high on the list. A reticulated hemoglobin content can also distinguish between iron deficiency and anemia of chronic disease.

https://www.uchealth.org/professionals/Documents/file-pdf/CLNLAB-2013-02-11-reticulated-hemoglobin-equivalent.pdf
2016-01-01 6:44 pm
360? 30 is normal. Magnets should stick to you.
2016-01-01 7:21 pm
You don't say what your haemoglobin and MCV are, but the likeliest cause of that is an acute phase response to illness. Ferritin rises in the presence of inflammatory disorders, commonly infection or diseases like rheumatoid arthritis.

Your transferrin saturation and serum iron means your ferritin doesn't indicate iron overload. 360 isn't *that* high, in diseases like haemochromatosis it's usually at least twice that.

C reactive protein would be a useful test here.

Doctor


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