黄連所分離的黃連素主要成分具有各種各樣的藥理活性, 包括治療神经退行病的阿尔茨海默疾病(AD)。黃連素通過抑制降低相關的酶與及氨基酸活性來預防阿尔茨海默病(AD)是已知的事情。不幸的是, 單一的黄連素化學結構並沒有顯著的調節功效。作為我们考慮的一部分, 本回顧文章對黃連素洐生物的基礎結構進行了化學合成和修飾研究。結果首次顯示(23), (10), (86), (52), 和 (61)的基礎結構具有潛在作用。
The major component of berberine from Coptis chinensis possesses variety of pharmacological activity, including neurodegenerative diseases with Alzheimer’s disease (AD) treatment. Therapeutic effect of berberine was known by inhibiting the relevant enzyme and amino acid to prevent (AD) disease. Unfortunately, the single of berberine compound in regulation of those has not significantly materialized. In order for us to consider in the section, the review paper to investigation in based structured by chemically modified and synthesis from berberine-derivatives. Results showed the potential effect in based structures of (23), (10), (86), (52), and (61) for the first time.
中譯英(修改英文). Thank you so much!
2014-06-09 3:47 am
回答 (1)
2014-06-09 4:25 am
✔ 最佳答案
Berberine Berberine separated main components have various pharmacological activities, including the treatment of neurodegenerative disease, Alzheimer's disease (AD). Berberine by inhibiting enzymes associated with reduced activity, and amino acids to prevent Alzheimer's disease (AD) is a known thing. Unfortunately, a single chemical structure of berberine and no significant adjustment effect. As part of our consideration of this review article on infrastructure berberine 洐 biological chemical synthesis and modification were studied. The results show for the first time (23), (10), (86), (52) and (61) having a potential role infrastructure.
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https://hk.answers.yahoo.com/question/index?qid=20140608000051KK00134