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DOWNTOWN
(noun, adjective, adverb) American English 市中心區, (尤指鬧市商業區)
- the centre of a city or town, especially the business and the shopping area where there are tall buildings, stores, offices etc.
We stayed at the hotel in the heart of downtown last summer.
(downtown ~ noun)
We met at a downtown restaurant yesterday.
(downtown ~ adjective)
I need to go downtown and get some stuff for the party.
(downtown ~ adverb)
MIDTOWN
(noun, adjective , adverb) American English 市中間地區 (商業區和住宅區的中間地區)
- the part of a city that is between central business area (downtown) and the outer parts (uptown).
UPTOWN
(noun, adjective, adverb) [大多數是住宅區]
- the upper part of a city or town, that are away from the centre, especially the one where the streets have large numbers in their names.
If you go uptown, or go to a place uptown, you go away from the centre of a city or town towards the edge.
參考: Oxford Advanced Learner's Dictionary