How do alcohol and chloroform damage cell membrane (urgent)?

2012-04-13 1:14 pm
How do alcohol and chloroform damage cell membrane? And why does paraffin oil have no effect on the permeability of cell membrane?

thanks

回答 (1)

2012-04-13 1:38 pm
✔ 最佳答案
Both Chloroform and alcohol are hydrophilic, because they have partial charges on the chlorine and oxygen atoms in their structure (due to differences in electronegativity between those atoms and carbon/hydrogen)

Paraffin oil is made up only of hydrocarbons, and since hydrogen and carbon basically have the same electronegativity, there will be no partial charges on any of the atoms. This makes paraffin oil hydrophobic.

Cell membranes are made up of phospholipid bilayer, which can be disrupted when surrounded by hydrophilic molecules such as chloroform or alcohol, but not by hydrophobic molecules like the hydrocarbons in parrafin.

To be brutally honest I do not know the exact affects on the cell membrane of alcohol and chloroform, other than they will cause it to be degraded. I hope this answer adequately explains why, at the very least!

Regards


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