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<Methyldopa> 子癇症首選藥物。 Methyldopa並不適合同時患有高血壓與憂鬱症的病人。Methyldopa or Alpha-methyldopa (brand names Aldomet, Apo-Methyldopa, Dopamet, Novomedopa) is a centrally-acting adrenergic antihypertensive medication. Its use is now deprecated following introduction of alternative safer classes of agents. However it continues to have a role in otherwise difficult to treat hypertension and gestational hypertension (formerly known as pregnancy-induced hypertension). 降血壓藥物,長期服用會有positive Coombs test,與免疫反應相關,例如:紅血球溶血反應。可經由decarboxylation再經hydroxylation而產生活性代謝物。