What does he look like? or What is he look like?

the correct version is "what does he look like"; "what does he look like so I'll recognise him in the bar?"
"what is he looking like" would be a better version of your other - but is subtly different; "what's he looking like in his wedding suit?" it indicates a temporary situation.

you can't say 'how does he look like?' it doesn't work. It will have to be 'What does he look like.'

It should be how does he looks like

What Does He Look Like

she is fat

What does he look like? is the right way to ask. and then the answer would be, He is tall and thin. what is he look like is the wrong grammar to use