Cut down certain food, still cholesterol?

Add exercise, that can help. Add wholegrain foods and soluble fiber. If your cholesterol is still high, there's a chance it's genetic. There's something called familial hypercholesterolemia, and no amount of lifestyle changes can lower your cholesterol sufficiently if you have it. Your doctor may want you to start on a statin in that case.

I am not sure that you have actually asked a question, you have listed what has happened to your husband, but not really said what you want to know? You have not given your husbands age, medical history or current medication history if there is one, nor said if he smoke, which would be a disaster and if he does should be the first thing to go. He appears from what you have said to have 3 risk factors:- Overweight, though you don't give the level. Raised blood pressure. Raised cholesterol. There are a number of things he can try and do to help himself, though they are unlikely to result in him avoiding medication if the problems are well established. They are all pretty obvious lifestyle changes. Moderate regular exercise 5 days a week, within the limitations currently imposed by his weight and his asthma. This would help him lose weight, it also lowers blood pressure and increases HDL cholesterol, the good cholesterol. A weight reduction diet, low in animal fats, this wold help weight loss, which helps lower blood pressure and help lower cholesterol. It would also reduce his future risk of diabetes, which is the next stage in what is often called 'the metabolic syndrome'. ( obesity, hypertension,hypercholesterolaemia, diabetes and heart disease, making up a composite disease entity.) Exercise would also help his asthma, make him fitter and more able to do more exercise and as an independent positive factor increase his lifespan. It is also a good idea to reduce salt intake. It is a bit of a tall order to get all these things right, but if you do the odds move in your favour!

Avoid alcohol, smoking, keep active (all these will also help reducing excessive weight).