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Scientific Research and Essay Vol.4 (7), pp. 705-709, July, 2009
Available online at
http://www.academicjournals.org/SRE
ISSN 1992-2248 © 2009 Academic Journals
Full Length Research Paper
Impact of polysaccharides from Cordyceps on antifatigue in mice
Tao Li *, and Wei Li
China West Normal University, Nanchong, Sichuan Province, 637002, People’s Republic of China.
Dezhou University, Dezhou, Shandong Province, 253023, People’s Republic of China.
Accepted 26 June, 2009
In this study, the anti-fatigue effect of the purified polysaccharides from Cordycep were evaluated in mice. Swimming endurance experiment of mice were carried out after 21 days of polysaccharides from Cordyceps administration. And Body weight, blood lactic acid, serum blood urea nitrogen and tissue glycogen levels of mice were determined. Results showed that polysaccharides from Cordyceps extended the swimming endurance time of mice, effectively delayed the increasing of blood lactic acid, increasing the storage of liver and muscle glycogen. The dosage of 200 mg/kg was more effective than any other dosage. The results suggested that polysaccharides from Cordyceps had significant antifatigue effects on mice.