Will David Ortiz going to retire Major League Baseball in the future?

No he will never retire in the future. Only in the past and maybe the present. But the chances of that are smaller

C.) STFU

Yes, he can't play forever. He has 3 years left in him, 4 max.
I think you should have worded your question differently...

of course we all gotta go some day

for infielders and outfielders I'd say about 42

but pitchers 44-47

Yes eventually all players retire even Phil Niekro and Satchel Paige retired eventually. Though I don't see him retireing for at least five years.

yes he will have to retire as do all of the players who dont play anymore