In and during

以下兩句例子及解釋，希望可以幫你。

A: Mr. Brown came to see you during your absence. ...

Meaning : while your were absent, while your absence was taking
place.
Shows duration.

B: Mr. Brown came to see you in your absence. ...

Meaning: when you were not present, in that situation when you
were not present.
Shows what happens in a certain state/situation, at a certain moment/
snapshot in time.