nucleophilic addition by CN-

2009-04-24 7:10 am
想問下點解
許nucleophilic addition to carbonyl compound
唔用HCN用KCN同H+
但係CN-唔會同H+combine埋變成HCN咩?

回答 (1)

2009-04-24 9:26 pm
✔ 最佳答案
冇錯,CN- 同H+ 係會readily combine to form CN-既
所以我地唔可以一齊加,要分開兩個step黎加~
考試要寫成: 1. CN- 2. H+
1. nucleopilic attack by CN- :
R2C=O + CN- --> R2(NC)CO-
2. protonation by acid:
R2(NC)CO- + H+ --> R2(NC)COH


2009-04-24 13:27:52 補充:
更正: 冇錯,CN- 同H+ 係會readily combine to form HCN既


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