我想問一下醫藥問題~~急急急~~

2009-02-25 3:39 am
我想問一下藥名: Librax 是什麼藥,是腸胃藥定係鎮定劑????因為我 search到唔同的答案.Thanks~~急急急急~~~Thanks!!!!!

回答 (4)

2009-02-25 8:31 pm
✔ 最佳答案
「Librax」則用於治療精神緊張,但其副作用會導致呼吸緩慢。
Chlordiazepoxide, is a sedative/hypnotic drug which is a benzodiazepine derivative and is marketed under the trade name Librax. It has a medium to long half life but its active metabolite has a very long half life. Chlordiazepoxide has amnestic, anxiolytic, hypnotic and skeletal muscle relaxant properties.
Chlordiazepoxide acts on benzodiazepine subreceptors of the main GABAA receptor and this results in an increased binding of the inhibitory neurotransmitter GABA to the GABAA receptor thereby producing inhibitory effects on the central nervous system and body similar to the effects of other benzodiazepines.[6] Chlordiazepoxide is anticonvulsant.[7]There is preferential storage of chlordiazepoxide in some organsincluding the heart of the neonate. Absorption by any administeredroute and the risk of accumulation is significantly increased in theneonate. The withdrawal of chlordiazepoxide during pregnancy and breastfeeding is recommended, as chlordiazepoxide rapidly crosses theplacenta and also is excreted in breast milk.[8] Chlordiazepoxide also decreases prolactin release in rats.[9] Benzodiazepines act via micromolar benzodiazepine binding sites as Ca2+ channel blockers and significantly inhibit depolarization-sensitive Calcium uptake in animal nerve terminal preparations. [10] Chlordiazepoxide inhibits acetylcholine release in mouse hippocampal synaptosomes in vivo. This has been found by measuring sodium-dependent high affinity choline uptake in vitro after pretreatment of the mice in vivo with chlordiazepoxide. This may play a role in chlordiazepoxide's anticonvulsant properties.[11]
2009-10-17 8:54 am
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2009-02-25 4:06 am
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2009-02-25 4:05 am
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