Do proteins denature at temperatures that are too cold?

Lower temperatures, but above freezing, stabilize proteins. At freezing and below, it's a different story.

low temperature denaturation of proteins - It has been observed that proteins can denature at low temperatures (less than 0oC), suggesting that nonpolar residues become more "soluble" in water at low temperatures (i.e. they move from the more hydrophobic interior of a protein to the more polar outside). Compare the solubility of nonpolar gases like CO2 or N2, which are more soluble at low temperature. As you heat solutions of nonpolar gases in water, the gases become less soluble as evidenced by bubble formation (i.e. phase separation of dissolved gases as they become more insoluble). If protein behavior is governed by this same behavior (greater solubility of nonpolar groups at low temperatures), it would suggest that proteins might denature at low temperatures (leading to increased exposure to water of the nonpolar side chains). This phenomena has been observed.

Yes they can as well as to hot or if something like salt concentration is to great. Some proteins can Re-nature meaning that they can adjust back into their workable structure again others, well they are just dead.

Yes, but it is typically at temperatures far below freezing.

Cold Denaturation

How would I know????

This Site Might Help You.

RE:
Do proteins denature at temperatures that are too cold?
Do proteins just denature at temperatures that are too hot or do they also denature at temperatures that are too cold?