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Summary 摘要
Patients with chronic obstructive pulmonary disease (COPD) often have difficulties with keeping their weight.

The aim of this investigation was to study nutritional status in hospitalised Nordic COPD patients and to investigate the association between nutritional status and long-term mortality in this patient group.

In a multicentre study conducted at four university hospitals (Reykjavik, Uppsala, Tampere and Copenhagen) hospitalised patients with COPD were investigated. Patient height, weight and lung function was recorded. Health status was assessed with St. George’s Hospital Respiratory Questionnaire. After 2 years, mortality data was obtained from the national registers in each country.

Of the 261 patients in the study 19% where underweight (BMI o20), 41% were of normal weight (BMI 20–25), 26% were overweight (BMI 25–30) and 14% were obese. FEV1 was lowest in the underweight and highest in the overweight group (p 0.001) whereas the prevalence of diabetes and cardio-vascular co-morbidity went the opposite direction. Of
the 261 patients 49 (19%) had died within 2 years. The lowest mortality was found among the overweight patients, whereas underweight was related to increased overall mortality.

The association between underweight in COPD-patients, and mortality remained significant after adjusting for possible confounders such as FEV1 (hazard risk ratio (95% CI) 2.6 (1.3–5.2)).


慢性阻塞性肺部疾病的病人通常無法維持體重。
這是調查位於北歐地區慢性阻塞性肺部疾病的住院病人在營養狀況和長期死亡率之關聯
這是四位醫學院的學生(Reykjavik, Uppsala, Tampere and Copenhagen)在醫院針對慢性阻塞性肺部疾病的住院病人所做的研究。病人的身高、體重及肺部的紀錄。身高情況的評估和喬治醫院的呼吸記錄。調查2年全國各地區的死亡率。
在261個病人中有19％體重不足（BMI＜20），41％正常體重（BMI 20～25），26％體重輕度過重（BMI25～30）和14％體重嚴重肥胖。體重不足的病人19％ 2年內死於COPD疾病。這可探討體重不足和體重過重對於COPD的死亡率。