inflammation

2008-07-25 10:24 am
點解inflammation一定係innate response (大部分textbook都咁寫)?

如果infection係antigen的話有沒有inflammation?

acute immune response和chronic immune response是否只是timing不同? 可不可以有野直接induce chronic immune response without acute immune reponse? both of them can be caused by innate and adaptive immune system?

Hope u guys can help me! Thx!

回答 (1)

2008-08-03 7:38 am
✔ 最佳答案
Innate immunity is immunity that you are born with.
Acquired immunity is immunity that develops with exposure to various antigens. Your immune system builds a defense that is specific to that antigen.
The inflammatory response (inflammation) occurs when tissues are injured by bacteria, trauma, toxins, heat, or any other cause. The damaged tissue releases chemicals including histamine, bradykinin, and serotonin. These chemicals cause blood vessels to leak fluid into the tissues, causing swelling. This helps isolate the foreign substance from further contact with body tissues.
上面綠色深色字所說的 release chemicals 是與生俱來的,無論之前有沒有 expose to the antigen. 所以是 innate immunity.
如果infection係antigen的話有沒有inflammation?
總之是 antigen 就能 induce inflammation response. 不過如果有 acquired immunity的人, 即係本身可以好快產生 antibody, 咁發炎會快D退,如果沒有 acquired immunity, 發炎會耐D,因為要等自己身體制造合適的抗體都需要時間。
acute immune response和chronic immune response是否只是timing不同?
我理解是反應的時間的長短,acute immune response是急性反應,是身體剛剛遇到antigen時的反應;chronic immune response是慢性反應,即是身體不能即時清除病源,反應在一段長時間內都沒消退。
可不可以有野直接induce chronic immune response without acute immune reponse?
如上所說是先有acute immune response,之後變成 chronic immune response。
both of them can be caused by innate and adaptive immune system?
At first time come across an antigen, initially the immune response must be the innate immune response. Later on, the adaptive immune response comes up which is much stronger and highly specific to the antigen, and this adaptive immunity is long lasting.

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