Horomones - hydrophilic and hydophobic properties - dicatate their purpose?

2008-05-19 12:44 pm
What are the three types of hormones and how do their hydrophilic and hydrophobic properties dictate their purpose.

I have to write a 2 page paper on this topic. If you could explain a bit and please have the links or book names you got the info from.

I know what the hydrophilic/phobic definitions are and I have the three types of hormones.
Hormones are categorized into three different hormones peptides, steroid, and amine.

MY MAIN PROBLEM OR HAVING TROUBLE EXPRESSING MYSELF IS THE FOLLOWING:
how do their hydrophilic and hydrophobic properties dictate their purpose.

Please help.. much appreciated! :)

I have about a page now.. so 1/2 way there! :)

Thanks again
更新1:

Thanks.. but I think checking wikipedia is what everyone does first! :)

更新2:

tally - that was great - do you have a link? i really need it! :) thx

回答 (3)

2008-05-19 2:23 pm
✔ 最佳答案
Their hydrophilic/hydrophobic properties dictate where they act- hydrophilic cannot cross cell membrane so work on membrane-bound receptors, resulting in second messenger cascades. These can for example activate an enzyme- fast acting.

Hydrophobic hormones can enter the cell and directly influence gene transcription, 'switching on' a gene, resulting in new proteins being synthesised- slower acting.

This means that speed and duration of action are both determined by hydrophobic/philic properties.

Does this help? Will try and find a credible link.
2008-05-19 9:17 pm
Hormone differs according to their target and distance they need to travel to their target. To classify hormones there are generally 4 kinds:

paracrine - target is nearby, maybe a number of cells away
autocrine - target is the cell that released the hormone, that's the target is itself
endocrine - hormone that is released into blood stream direcly
exocrine - hormone that is secreted into a duct and there wait for a signal to release it

hydrophilic vs hydrophobic hormone is dependent on its target. If the target it intracellular (inside a cell), then the hormone needs to travel into the cell through the cell membrane which is hydrophobic. So a hydrophobic hormone would be best for this purpose because then it can get through the hydrophobic plasma membrane and get to its target. Conversely, a hydrophilic hormone is one that cannot get through the plasma membrane easily and therefore is best for targeting receptors on the surface of cells.
參考: wikipedia and myself
2008-05-19 8:29 pm


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