Are they middle level manager ?

They are a middle or higher level of the Management Team. Regional Manager is looking after the georgraphic district or area managerment issues. This is a very high level. The project leader is managing a project or job. The palnt Manager is we usually call Factory Manager or Production Manager.

They are all the managers at middle level as all are functional & operating managers
High level managers are those mangers representing share holders' interests and directors of the board to performing corporate Strategy
such as buy-out, M&A, investments, restructuring & right sizing of organization, long-term corporate development and planning.
For example the positions with the title of CEO, COO, CFO, CTO, President, VP, MD and the like all are top managment.