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That yawn was the first sign that you're not so awake as you think. After about 18 hours without sleep, your reaction time begins to slow from a quarter of a second to half a second and then longer. If you're like most people, you will start to experience bouts of microsleep—moments when you zone out for anywhere from two to 20 seconds and drift out of your lane or find that you have to keep rereading the same passage. Your eyelids start to droop more severely, and by the 20-hour mark you begin to nod off. Your reaction time, studies show, is roughly the same as someone who has a blood-alcohol level of 0.08—high enough to get you arrested for driving under the influence in 49 states. You forget to do things like double-check the spelling of a name or set the brake when you stop on a hill.