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Yamanouchi Obtains Approval for the Orally Disintegrating Tablet Harnal D Tablet, a Treatment for Functional Symptoms of Benign Prostatic Hyperplasia, in Japan






Tokyo, Japan, Sept 22, 2004 - (JCN Newswire) - Yamanouchi Pharmaceutical Co., Ltd. announced that it obtained approval for Harnal(R)D Tablet 0.1mg/0.2 mg, an additional dosage form for the treatment for functional symptoms of benign prostatic hyperplasia Harnal (generic name: tamsulosin HCl), in Japan.

Harnal D Tablet is an orally disintegrating tablet developed using Yamanouchi's proprietary drug delivery technology WOWTAB*1. It can be ingested without water since it quickly disintegrates upon contact with saliva in the mouth. It can be easily taken even by elderly patients and patients with impaired swallowing function. It is also useful for patients with restricted water consumption and meets various needs of patients

Harnal is an alpha-1 blocking agent with a great selectivity for prostatic and urethral smooth muscles. It improves the functional symptoms of benign prostatic hyperplasia by relaxing the urethra with almost no effect on vascular smooth muscles, which affect blood pressure. It is now marketed in 65 countries including Japan, the US and European countries, and its efficacy and safety are highly appreciated.

In addition to Harnal D Tablet in Japan, Yamanouchi plans to launch the long-lasting controlled release formulation YM617 TOCAS*2 in Europe. Yamanouchi will continue to maximize the value of Harnal by marketing these new formulations.
http://www.japancorp.net/Article.Asp?Art_ID=8357
In US Tamsulosin (rINN) (IPA: ) is an ?1a-selective alpha blocker used in the symptomatic treatment of benign prostatic hyperplasia (BPH). Tamsulosin was developed by Yamanouchi Pharmaceuticals (now part of Astellas Pharma) and is marketed by various companies under licence, including Boehringer-Ingelheim and CSL. As of 2006, tamsulosin hydrochloride extended-release tablets are marketed under the trade name Flomaxtra. It was formerly marketed as modified-release capsules under the trade name Flomax.

圖片參考：http://www.drugs.com/pdr/images/P05309C2.jpg

http://www.drugs.com/pdr/flomax.html