chem---optical activity

2007-05-13 11:24 am
Is dopamine optically active ?? Explain your answer.

The structure of dopamine:
http://en.wikipedia.org/wiki/Image:Dopamine2.svg

回答 (2)

2007-05-13 9:28 pm
✔ 最佳答案
The structure of dopamine cannot be found by the above link, but can be found in the following webpage :
http://www.biopsychiatry.com/dopamine/dopamine.jpg


圖片參考:http://www.biopsychiatry.com/dopamine/dopamine.jpg

Dopamine is optically inactive, because there is no chiral carbon atom (sp3 carbon atom with 4 different groups/atoms attached to it) in its molecule.
2007-05-13 9:34 pm
no.
to determine whether a compound is ooptically active, both of the following criteria should be fulfilled

1)the existence of sp3 hybridised carbon:
it is possible only for sp3 to give a chiral centre.
2)the existence of chiral centre:
if the four substituent group of a sp3 carbon is different from each other, it is a chiral centre

there are only two sp3 carbon on the long carbon chain binded with amino group (-NH2)
however, both of them are respectively binded with two same H- group.

only criterion (1) is fulfilled. the compound is not optically active.
參考: myself


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