temperature will be one problem. Battery life is usually the big problem. You may need extra battery and ways to keep your DC warm between shoots.If you have manual camera, better to bring one with you and some film.
It is always the best to have 2 cameras if you are really keen to capture some picture for memory.
I remember for most of the major trip I went, I always brought 2 cameras.
Also, if you are moving from cold place to indoor (which is warm), wait the camera to get warmer naturally before you open it, moisture may condense on the surface of the lens if you open it immediately.(the lens will be a good smooth cold surface for condensation.