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Guangzhou became a part of China in the 3rd cent B.C (do you mean 3BC = 3 yrs before christ? or do you mean in the Third century (201AD - 299AD)? 'cos you cannot use both at the same time)
Hindu and Arab merchants reached Guangzhou in the 10th century. It was not for long before Guangzhou became the first Chinese port regularly visited by European traders. Portugal was the first country to fasten a trade monopoly in 1511; however, it was broken by the British in the late 17th century.
Moreover, French and Dutch were admitted in the18th century. Up until now,Guangzhou has a history of more than 2,800 years in trading industry (or: in trading with foreign countries).
In Modern history, Guangzhou was the seat of the revolutionary movement under Sun Yat-sen in 1911; the Republic of China was announced there that year. Guangzhou was briefly a location of one of the earliest Communist communes in China in 1927.