The blood is pumped by three separate hearts, two of which are used for pumping blood to the cuttlefish's pair of gills (one heart for each gill), and the third for pumping blood around the rest of the body. A cuttlefish's heart must pump a higher blood flow than most other animals because hemocyanin is substantially less capable of carrying oxygen than hemoglobin.
The blood of a cuttlefish is an unusual shade of green-blue because it uses the copper-containing protein hemocyanin to carry oxygen instead of the red iron-containing protein hemoglobin that is found in mammals.
大意是兩個鰓分別由兩個心臟供血,第三個心臟供應身體血液,要三個心臟是因牠們的藍綠色的血液送氧能力較一般動物紅色的血液為低,惟有利用三個心臟去增加血液流量,將勤補短。