what causes sickle cells?

a mutation which changes the 6 th amino acid in the the protein made up of 146 amino acid found in haemoglobinn

english royal family has such illness, that's why many royal family members die very early

sickle cells are differ from, normal human red blood cell. sickles cells have less surface area, so less oxygen can be transported. the patient suffer from sickle cells may always feel fainting because oxygen is insufficent